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Amtolmetin guacil
- NameAmtolmetin guacil
- CAS87344-06-7
- Purity99%
Product Details
Factory supply Amtolmetin guacil 87344-06-7 with sufficient stock and high standard We supply high quality Amtolmetin guacil (CAS 87344-06-7), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the Amtolmetin guacil ?
Amtolmetin guacil is white needle-shaped crystal, while it's Molecular Formula is C24H24N2O5. Analgesic; anti-inflammatory used in the treatment of rheumatoid arthritis,
What is the CAS number for Amtolmetin guacil ?
The CAS number of Amtolmetin guacil is 87344-06-7.
More information of Amtolmetin guacil 87344-06-7 are:
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Synonyms |
Glycine,N-[[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetyl]-, 2-methoxyphenyl ester(9CI);Amtolmethin guacil;N-((1-Methyl-5-p-toluoylpyrrol-2-yl)acetyl)glycine o-methoxyphenyl ester;Amtolmetin guacyl;MED 15;ST 679;2-Methoxyphenyl 1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate; |
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CAS?Number |
87344-06-7 |
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Molecular Formula |
C24H24N2O5 |
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Molecular Weight |
420.465 |
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Density |
1.19 g/cm3 |
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Melting Point |
116-119 °C |
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Boiling Point |
663.3 °C at 760 mmHg |
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Flash Point |
354.9 °C |
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PSA |
86.63000 |
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LogP |
3.22830 |
What is Amtolmetin guacil (87344-06-7) used for?
Amtolmetin guacil is an orally active non-steroidal antiinflammatory drug (NSAID) introduced for the treatment of osteoarthritis, rheumatoid arthritis and post-operative pain. Amtolmetin guacil is reported to elicit a more rapid and improved analgesic action than other agents such as paracetamol. In models of adjuvant arthritis and rheumatic diseases, amtolmetin guacil is more efficacious than existing drugs such as naproxen, indomethacin and piroxicam. As a non-acidic prodrug of tolmetin, it has similar in vivo activity to the parent but with minor ulcerogenic action, lower acute toxicity, and excellent biological and gastric tolerability.
InChI:InChI=1/C24H24N2O5/c1-16-8-10-17(11-9-16)24(29)19-13-12-18(26(19)2)14-22(27)25-15-23(28)31-21-7-5-4-6-20(21)30-3/h4-13H,14-15H2,1-3H3,(H,25,27)
Articles related to Amtolmetin guacil:
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Article |
Source |
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Synthesis and process optimization of amtolmetin: An antiinflammatory agent |
Reddy, Lekkala Amarnath,Chakraborty, Saurya,Swapna, Rodda,Bhalerao, Dinesh,Malakondaiah, Golla China,Ravikumar, Mylavarapu,Kumar, Abhijeet,Reddy, Gade Srinivas,Naram, Jyothirmayi,Dwivedi, Namrata,Roy, Arnab,Himabindu, Vurimidi,Babu, Bangaru,Bhattacharya, Apurba,Bandichhor, Rakeshwar experimental part, p. 362 - 368 (2011/03/21) |
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