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1,2,5,8-Tetrahydroxyanthraquinone

  • Name 1,2,5,8-Tetrahydroxyanthraquinone
  • CAS 81-61-8
  • Purity 99%
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Product Details

Purity 99% Min 1,2,5,8-Tetrahydroxyanthraquinone 81-61-8 Spot Supply with Safe Transportation

  • Molecular Formula: C14H8O6
  • Molecular Weight: 272.214
  • Vapor Pressure: 2.59E-11mmHg at 25°C 
  • Melting Point: >275° 
  • Refractive Index: 1.814 
  • Boiling Point: 517.1 °C at 760 mmHg 
  • Flash Point: 280.6 °C 
  • PSA: 115.06000 
  • Density: 1.781 g/cm3 
  • LogP: 1.28440 

1,2,5,8-Tetrahydroxyanthraquinone(Cas 81-61-8) Usage

Preparation

Quinalizarin. 1,2-Dihydroxyanthracene-9,10-dione or 1,4-Dihydroxyanthracene-9,10-dione with great excess fuming sulfuric acid oxidation and hydrolysis.

Biochem/physiol Actions

Quinalizarin is a potent (IC50 = 110 nM), ATP-competitive, and highly selective (IC50 >1μM against CK1 and 72 other kinases) casein Kinase II (CK2) inhibitor.

Standard

Ironing Fastness

Alkali

Acid

Purification Methods

Crystallise the quinone from acetic acid or nitrobenzene. It can be sublimed in vacuo. The Cu salt forms red crystals. [Beilstein 8 H 549, 8 I 755, 8 II 584.]

Definition

ChEBI: A tetrahydroxyanthraquinone having the four hydroxy groups at the 1-, 2-, 5- and 8-positions.

Properties and Applications

violet (chromium), dark red light purple (aluminum). Soluble in ethanol. In concentrated sulfuric acid for blue purple, dilution after dark red precipitation. Standard Ironing Fastness Light Fastness Fulling Persperation Fastness Soaping Water Alkali Acid ISO 6 4-5 5 4-5

InChI:InChI=1/C14H8O6/c15-6-3-4-7(16)11-10(6)12(18)5-1-2-8(17)13(19)9(5)14(11)20/h1-4,15-17,19H

81-61-8 Relevant articles

Method for dyeing keratinous fibres using a monohydroxyindole or dihydroxyindole and a non-oxidizing aromatic carbonyl derivative and dyeing agent

-

, (2008/06/13)

The present invention relates to a metho...

One-Electron Redox Potentials of Phenols. Hydroxy- and Aminophenols and Related Compounds of Biological Interest

Steenken, S.,Neta, P.

, p. 3661 - 3667 (2007/10/02)

The rate constants for reversible electr...

81-61-8 Process route

1,2-dihydroxy-9,10-anthracenedione
72-48-0,84754-86-9

1,2-dihydroxy-9,10-anthracenedione

1,2,5,8-tetrahydroxy-anthraquinone
81-61-8

1,2,5,8-tetrahydroxy-anthraquinone

Conditions
Conditions Yield
With sulfuric acid; at 25 - 50 ℃; man giesst dann auf Eis und loest den aus dem Schwefelsaeureester bestehenden Niederschlag in Natronlauge; die alkal.Loesung kocht man mit ueberschuessiger Salzsaeure;
With sulfuric acid; at 25 - 50 ℃; man giesst dann auf Eis und loest den aus dem Schwefelsaeureester bestehenden Niederschlag in Natronlauge; die alkal.Loesung kocht man mit ueberschuessiger Salzsaeure;
3,4-dimethoxy-phthalic acid
518-90-1

3,4-dimethoxy-phthalic acid

hydroquinone
123-31-9,8027-02-9

hydroquinone

1,2,5,8-tetrahydroxy-anthraquinone
81-61-8

1,2,5,8-tetrahydroxy-anthraquinone

Conditions
Conditions Yield
With sulfuric acid; at 130 ℃; man verseift den entstandenen Dimethylaether mit Eisessig-Chlorwasserstoff bei 200grad;

81-61-8 Upstream products

  • 14597-12-7
    14597-12-7

    3,6-dimethoxyphthalic anhydride

  • 120-80-9
    120-80-9

    benzene-1,2-diol

  • 81-64-1
    81-64-1

    1,4-dihydroxy-9,10-anthracenedione

  • 72-48-0
    72-48-0

    1,2-dihydroxy-9,10-anthracenedione

81-61-8 Downstream products

  • 61169-36-6
    61169-36-6

    1,2,4,5,6,8-hexahydroxy-9,10-anthraquinone

  • 6373-25-7
    6373-25-7

    1,2,4,5,7,8-hexahydroxy-anthraquinone

  • 5413-65-0
    5413-65-0

    1,2,4,5,8-pentahydroxy-9,10-anthraquinone

  • 120951-83-9
    120951-83-9

    1,2,5,8-Tetrakis-benzyloxy-anthraquinone

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